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Dairy products intolerance real, “not in someones heads” – Medical Xpress

A study participant takes her milk “challenge. ” Credit: University of Auckland

For the first time, scientists have shown that dairy intolerance is really a physiological condition distinct from lactose intolerance, and not “all in people’s heads”.

“Lots of people suspect that they have some intolerance to dairy foods, yet testing shows they aren’t lactose intolerant, ” says Dr Emerald Milan, a research fellow at the Liggins Institute, University of Auckland, New Zealand. “Before this study, presently there had not been any detailed analysis associated with dairy intolerance to see if another thing could be causing it.

“Our findings show dairy intolerance is a ‘real thing’ with a specific symptom profile – not something that’s just in people’s mind. That means sufferers and doctors may better identify it. Now, we have to find out more about what’s going on and how to measure it better. ”

The girl team gave 30 healthy women who reported being dairy intolerant, and a control group of 10 dairy-consuming women, two “challenges”: drinking 50g of lactose – an comparative amount of the poorly digested sugars naturally occurring in about a litre of milk – to determine if they had lactose intolerance or not. On a separate visit, the same women downed 750ml of standard dairy milk. The women were aged 20-30, and had BMI within the normal range.

The researchers closely tracked each woman’s digestion and metabolism from the milk with a battery of lab tests. Immediately after the women consumed the dairy, and at 30 minute intervals for three hours, the researchers took bloodstream, urine and breath samples, assessed their waist, and performed MRI scans. The women also recorded the way they felt.

Two specific patterns of symptoms emerged. The clearest difference was that the soreness and other symptoms came on plus subsided sooner in dairy intolerant women, suggesting the underlying issues happened in the stomach; while lactose intolerant women experienced their symptoms over a longer period, suggesting the trouble came about when lactose arrived in their small intestines.

The lactose intolerant women experienced flatulence, tummy rumbling and cramping – all of the symptoms used in a standard checklist for diagnosing the condition. Many of these symptoms had been experienced around two hours right after drinking the lactose or whole milk. The hydrogen levels in their breathing samples also peaked at two hours, up to 10 times over their baseline. Breath hydrogen is really a by-product of the gut bacteria digesting any lactose that isn’t absorbed by body, and is partly responsible for symptoms like bloating and flatulence.

The dairy intolerant women, like the lactose intolerant women, experienced acute stomach discomfort, including bloating and distension. The difference was that they experienced this pain and flatulence within 30-60 a few minutes, and without any cramping. These symptoms happened without any signs of malabsorption, such as elevated breath hydrogen.

“With these women, it was as if their particular stomachs weren’t digesting the whole milk as quickly. We need more research to spot exactly what’s going on, but we know that some nutrients affect the speed of digestion, like fibre or the type of protein; as can the release of hormones, like insulin and appetite hormones, ” says Dr Milan.

Early analysis of the biological measures offers some exciting leads. The dairy intolerant group, but not the lactose intolerant or control team, had a drop in blood sugar throughout the time that they felt most soreness (60 minutes).

“This is partly because the lactose intolerant group isn’t able to digest the particular sugar in milk and so their blood sugar changes less, but we need to do further analysis to understand the between the dairy intolerant and understanding groups, ” says Dr Milan.

Researchers have also determined some trends in several different chemical substances in the breath between the lactose and dairy intolerant groups. “If more work confirms these differences, it may allow us to create a breath check to determine if people are intolerant to aspects of dairy, like we presently do for lactose using breath hydrogen, ” she says.

Another finding was that some of the women who reported having simply no issues with milk were discovered to become lactose intolerant. “It may be that lactose intolerance lies on a spectrum, rather than everyone experiences extreme discomfort, inch says Dr Milan.

Lactose is digested by an enzyme produced in the small intestine. Generally your body stops making this enzyme after weaning off breast milk, however lots have the genetic ability to continue creating enough enzymes to digest lactose as long as they keep consuming dairy products. Genetic analysis is planned within this study to see if there is a genetic basis for dairy intolerance like there is for lactose intolerance.

Interestingly, some women had a 10-15 percent increase in waist circumference (up to 10 cm), but general there was no difference in waistline size changes between the study groups. The average increase across all ladies was 2-4 cm.

“You can have a healthy diet without dairy products, but many people enjoy dairy products — some of the dairy and lactose intolerant women in our study still got foods like yoghurt and parmesan cheese, despite the discomfort it caused them, ” says Dr Milan.

“Dairy is ubiquitous in the Western diet. It’s also a great source of calcium, protein and other nutrients. If we can better understand why some people have a problem with dairy, we can help make recommendations for all of them that are suited for their particular problem. inch

Explore further: Researchers find lactose intolerance related to low vitamin D levels


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Test Results Demonstrate Reductions in Lactic intolerance… – Pharmaceutical Processing

Pharmaceutical Digesting
Trial Results Demonstrate Reductions in Lactose Intolerance…
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Ritter Pharmaceuticals reports more analysis from its Phase 2b/3 test results demonstrating significant reductions within lactose intolerance symptoms.
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Story prebiotic shows continued reductions within lactose intolerance… – Healio

Pharmaceutical Digesting
New prebiotic shows continued reductions in lactose intolerance…
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RP-G28, a novel non-digestible oligosaccharide designed to stimulate the belly microbiota to metabolize lactose, considerably reduced symptoms in patients with …
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Ritter Pharma (RTTR) Reports Additional Phase 2b/3 Trial Results Analysis Showing Significant Reductions in… – StreetInsider. com

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The Phase 2b/3, multi-center, randomized, doubled-blind, placebo-controlled, parallel-group trial in 377-subjects was designed to determine the efficacy, safety, and tolerability of two dosing regimens of RP-G28 in subjects with lactose intolerance . RP
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Western Medicines Agency – News plus Events – CMDh confirms… : EU News


European Medicines Agency – Information and Events – CMDh verifies…
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The CMDh 1 has endorsed the particular recommendation of EMA' s Pharmacovigilance Risk Assessment Committee (PRAC) that will methylprednisolone injections …

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The way to Tell If You’re Lactose Intolerant or If It’s Something Else | SELF – SELF

If milk messes with your stomach, you might just believe you’re lactose intolerant and call it up day. But that’s not the only cause of dairy trouble, and knowing precisely why milk does a number on your stomach will help you get a better handle on the symptoms.


First stuff first: Lactose intolerance isn’t the same thing as a milk allergy.

“Lactose intolerance is the inability to digest lactose, which is the sugar in milk. An allergy to whole milk is basically your immune system reacting to the proteins in milk, not the particular sugar, ” James R. Baker, Jr., M. D., professor emeritus from the University of Michigan and CEO and CMO of Meals Allergy Research & Education, informs SELF.

With lactose intolerance, your body essentially has an enzyme insufficiency. It doesn’t make enough lactase—an enzyme in your small intestine in order to your body break down the sugar within milk. As a result, undigested lactose gets to your colon, where it responds with gut bacteria. This digestive misstep can then lead to stomach discomfort.

A milk allergy, on the other hand, means your immune system went awry. It attacks milk proteins—namely, casein and whey—when they get into your body. It sees these aminoacids as potential threats. Your body might respond by producing chemicals called histamines, prompting an allergic reaction.


Your symptoms will provide a significant clue about what’s troubling you.

People with a whole milk allergy often have an immediate reaction, within minutes. “Symptoms include mild ones such as skin rashes, hives, itching, and stomach pain. But they can also be serious, such as trouble breathing and poor blood circulation, ” Scott H. Sicherer, M. D., professor associated with pediatrics, allergy, and immunology at Icahn School of Medicine on Mount Sinai, tells SELF. Actually a food allergy can be life-threatening. It can result in anaphylaxis, a serious allergic reaction. And depending on your immune system, it might take only a dab of dairy products for it to happen.

Associated with lactose intolerance often take longer to manifest—from many minutes to hours. That’s because it takes time for lactose to go through your gastrointestinal tract and reach your colon. Once it does, you may experience gas, bloating, an upset stomach, and diarrhea. These symptoms may be uncomfortable, but they aren’t life-threatening. And the severity usually depends on just how much lactose you consume.


Your age is another indicator.

Another possible clue to your dairy problem is when you first started having symptoms. Most people with a milk allergy develop it as a child and outgrow it. Developing a food allergy as an grownup is pretty uncommon. “Usually by the time you happen to be an adult, your immune system has categorized itself out so it doesn’t respond to things like food, ” Dr . Baker adds.

So it’s much more likely that a recently noted dairy reaction was lactose intolerance. Some people—about 10-15 percent in the U. S. —develop this problem. The exact reason is not clear, but “we know with getting older the gut’s physiology declines, ” Gerard E. Mullin, M. M., a board-certified gastroenterologist and connect professor of medicine at The Johns Hopkins Hospital, tells SELF.


And your family tree may provide some insight.

Allergies and lactose intolerance can be passed on through families. You may be more prone to developing a food allergy if family members have allergies, too. That includes any kind of allergy, such as hay fever or even eczema.

A fall in lactase is often genetic, although it may sometimes be caused by problems in the small intestine, such as contamination. Certain groups of people are more likely to are afflicted by lactose intolerance, including African-Americans, Hispanics, American Indians, and Asian Americans.


So what should you do if dairy is wreaking havoc on the gut?

The only way to be certain about what’s causing your a reaction to dairy is to see your doctor. He or she will be able to make a diagnosis after inquiring about your symptoms and performing certain tests. To check for a dairy allergy, your doctor may take a test or prick your skin and put several milk on it to see if there is a chemical reaction. You may also be asked to eat some dairy in your doctor’s office. A breath test or stool example may be used to diagnose lactose intolerance.

Your doctor will also be able to rule out other potential digestive problems that may be exacerbated merely by dairy, such as irritable bowel syndrome (IBS). Regulations Dr . Mullin, “IBS is known for lactose-triggering symptoms due to the massive sugar content of lactose, which is often highly fermentable by gut bacterias, producing gas, bloating and diarrhea. ”


Once you know the reasons dairy is screwing with your stand, you’ll probably need to adjust your diet plans accordingly.

If you have virtually any milk allergy, you may need to completely shun foods that contain the milk vs casein and whey. Check the ingredient lists if you are shopping and ask questions when eating out. Your doctor may also give you an epinephrine auto-injector in case of a serious reaction.

With lactose intolerance, eating modest amounts of dairy may help alleviate the symptoms. Plus, some dairy foods, as with hard cheeses or goat’s of milk, may contain lower levels of lactose, so they may not bother you that much. An over-the-counter lactase pill may also be helpful you digest dairy, though these products usually are not effective in all people. If you have rigorous lactose intolerance, you may need to do away with dairy 100 %. Also take note that lactose can sometimes hide in some medicines, such as birth prevention pills and antacids.

And keep in mind, when limiting dairy products foods you may not get enough calcium mineral and vitamin D, which are important for preventing osteoporosis. So be sure to ask health care provider about other sources of calcium measurements into your diet, or if they would suggest a calcium supplement.

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Lactic intolerance Versus Milk Allergy: The Difference Worth… – NDTV

Lactose Intolerance Versus Milk Allergy: The Difference Worth Knowing

Highlights

  • The most common cause of milk intolerance is lactase insufficiency
  • Lactose intolerance is generally a benign condition
  • Milk gets a top spot in the list associated with common food allergens after peanuts

Based on the Asthma and Allergy Foundation associated with America, children happen to be most prone to developing various types of allergies. Talking of food allergies, milk gets a top place in the list of common food contaminants in the air right after peanuts. If you among those whom just can’t get along with milk or dairy products, should you call it an allergic reaction or lactose intolerance? For a layman both conditions are used interchangeably, which experts brand name as a case of severe lack of information. This piece sets out to comprehend milk allergy and lactose intolerance and straightforward ways to differentiate between the two.

Allergy versus intolerance

Allergy to any meal would translate to the body’s a reaction to any agent or compound found in the food item which the body interprets as an allergen; it involves the immune system. Intolerance with respect to milk or dairy comes from the body’s inability to produce an enzyme called lactose, which is used in wearing down the sugar and lactose content found in milk and dairy; it calls for the digestive system.

“Lipase is an enzyme which is critical for milk absorption. Over time most of us stop making this enzyme hence whole milk isn’t tolerated well as a result of which we develop acidity or gastrointestinal discomfort, leading to lactose intolerance. Milk allergy, on the other hand, can happen due to many factors like adulterated milk, etc . Usage of antibiotics on farm animals or homogenisation may kill important enzymes in milk that aid in busting milk protein, thereby causing allergic reaction, ” noted Shilpa Arora ND, a renowned Health Practitioner, Nutritionist and certified Macrobiotic Health Coach.

“The most common cause of milk intolerance is lactase deficiency, which is mostly acquired during late childhood or adulthood. It has high ethnic predilection, being highest in dark-skinned populations and lowest in north Europeans. Lactose intolerance is generally a benign condition, with symptoms limited to the gastro-intestinal tract, yet the primary obtained type lasts for a lifetime, ” claims US National Library of Medicine, National Institutes of Health.

Photo Credit: Dairy is a rich source of carbohydrates and proteins

Differing symptoms

A lactose intolerant person and a person along with dairy allergy would probably experience the same symptoms such as nausea, diarrhea, abdominal cramps and pain, gas and bloating. However , the latter group could also experience skin rash, swollen lip area, breathing trouble, wheezing and inflamed face among other reactions.

Diagnosis

If you think you might be lactose intolerant or suffer from milk allergy, visit your nearest hospital to explore various ways through which you can get tested and diagnosed for it. A simple lactose intolerance test or a hydrogen breath tests are a handful of most commonly used methods to diagnose lactose intolerance. Milk allergy is usually established simply by running a host of blood exams or through a simple skin prick test.

Management

Lactose intolerant people can take the sigh of relief as the situation can be managed better than the allergy. You can have a chat with your doctor about lactase enzyme supplement and incorporate into your diet to tolerate milk products better. Lactose-free products taste almost exactly the same, are fortified with nutrients and safe to consume. Experts suggest switching in order to yogurt and fermented milk products if the system supports them well. Many other ingredients like soy also consist of enough calcium to meet your dairy requirement.

People with milk allergy, on the hand, need to completely check food labels and avoid all-things-dairy, or anything that can remotely include traces of dairy.

“In case of lactose intolerance, switching to curd is the best bet as it boosts gut bacteria plus facilitates better absorption of calcium mineral, ” concluded Shilpa.

Always consult a certified medical specialist before jumping to conclusions or even making any dietary swaps.

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FIRST: Lactose Intolerance – What to and what not to eat – Malta Independent Online


Lactose intolerance is becoming a disorder that more and more people are becoming aware of. All those affected are not able to consume milk glucose – lactose – because their particular intestines do not either produce adequate quantities of – or absence altogether – the enzyme known as lactase.

The consumption of milk, and milk products, usually leads to serious complaints such as stomach pain, bloatedness and diarrhoea. But subtle signs and symptoms such as headaches, dizziness and chronic fatigue can also be the result of lactose intolerance. Since the symptoms are very unspecific and flexible, many people do not even know that they may be among those affected. Lactose intolerance is not a good allergy or disease, but knowing the symptoms and how to counteract them is essential for overall health and well-being.

So what can you do about it?

The symptoms of lactose intolerance can be alleviated by a change in diet or simply just the avoidance of anything that contains lactose. It is also possible to take enzyme preparations immediately before eating or drinking anything containing lactose. These products increase well-being without the need for changing your diet too much, but they only lead to relief – and not the disappearance of the symptoms. As a rule, a zero-lactose diet is preferable. Remember, lactose is found in many foods that you might not be aware of, so it is important to always read the labels!

In what will I find lactose?

In addition to normal dairy products such as milk (including compacted and dried), cream, butter, buttermilk, yoghurt (including kefir), whey, curd and cheese, you will find lactose on the list of ingredients with the following terms: milk, whey powder, whole milk or skimmed milk powder, and anything that starts with “lact-“.

Given that lactose belongs to the group known as ‘main allergens’, it has to be labelled accordingly when it is used in a product. It is therefore possible to see from the list of ingredients regardless of whether something contains lactose or dairy. Lactose can also be found in the following meals:

  • Bread, progresses, cakes and pastries and waffles
  • Ready-made meals, pizzas and preserves
  • Rich and creamy vegetables, casseroles, soups, grills and salads
  • Potato arrangements, puree powders, croquettes and chips
  • Deli meats, sausages and stews
  • Your favorite ice cream, chocolate, nougat, chocolates, muesli, cereals, caramel and sweets in general
  • Instant soups, instant gravies and instant creams
  • Infant milk food and probiotic food
  • Drugs, including supplements
  • Flavouring and spice mixes
  • Goats plus sheep milk, which also consist of milk sugar and is therefore no alternative

If it is difficult for you to completely remove milk products from your diet, you can try to establish just how much lactose is tolerated and combine this amount with other food during the day. A food journal is very important.

If, however , you do choose to remove all problematic foods out of your diet, be careful not to develop a calcium insufficiency. You can either switch to lactose-free whole milk, for example or – if you decide to use rice or nut milk — make sure they are calcium fortified. Increasing the amount of green vegetables you eat should also make sure that you are getting enough calcium.

There are numerous great alternatives to dairy products which are very healthy. So give whipped coconut cream a go – from the fantastic addition to desserts!

angelamallia. com

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Bloating update: Irritable bowel syndrome, important oils for bloating, and lactic intolerance – Bel Marra Health

By: Bel Marra Health | Colon Health | Sunday, July 16, 2017 – 05: 00 AM


IBS and bloating Emotions of bloating often leave you unable to button your pants as your belly grows in size and you feel sluggish. It’s possible that it could merely be something you ate that’s making you feel this way, but all you know is that you feel uncomfortable.

Bloating can occur for many different reasons, so to get you more acquainted with the subject, we have compiled a list of our own most informative articles on the subject. You will discover useful information on bloating and its relation to irritable bowel syndrome and lactose intolerance. We have also included treatment options by means of essential oils for bloating.

Irritable intestinal syndrome (IBS) and bloating might be caused by gut microbiota alterations and specific diets. Researcher Professor Giovanni Barbara said, “Contrary to this watch, recent findings suggest that IBS is usually linked to clearly detectable gut microbiota alterations. Additionally , bloating can be related to specific kinds of diet, thus opening up promising paths towards an efficient condition management. ”

IRRITABLE BOWEL SYNDROME is the most common gastrointestinal disorder impacting 20 percent of the western population. Symptoms of IBS include abdominal discomfort, bowel movement discomfort, and bloating. Bloating has been found to be the most bothersome symptom among IBS patients. Continue reading…

Do you suffer from bloating, gas, constipation, or diarrhea? If you do, you’re not by yourself. Many adults find that their bellies and digestive systems as a whole just aren’t what they used to be. This leaves them feeling uncomfortable and slow.

Although digestive problems could be caused by an illness, in many cases, it’s the lifestyle that contributes to bloating, gas, and changes in bowel movements. The following seven causes of digestive issues may help you regain control of your digestive system. Continue reading…

From time to time, we all move gas. Flatulence is a completely normal portion of the digestive process. When we digest food, it is reduced to its molecular form—this also results in the release associated with hydrogen, methane, and carbon dioxide gas that needs to be expelled from the body somehow. Luckily for us, our digestive tract is situated in a way that gas can be released, under your own accord or not. This helps relieve bloating, soreness, and pain associated with gas build-up.

However , sometimes we want a bit of help to get the gasses moving, as holding it in can be particularly uncomfortable. The use of stretching exercises such as yoga can help promote intestinal mobility, helping ease flatulence release. Roles to relieve gas help keep you normal and avoid that bloated feeling. Continue reading…

We all get bloated every now and then. We feel sluggish, are not motivated to do anything, and even have trouble buttoning up our pants due to the fact our stomach has grown in size. Whilst uncomfortable, bloating can be the result of any number of things, from the food we eat in order to hormonal fluctuations of your bodies.

Sometimes bloating can cause us to experience pain due to gas build-up, but other times, it may be due to causes that we can’t quite put our finger on.

Fortunately, through the use of essential oils for bloating, you can help relieve your pain. The following are five essential oils you should attempt today. Continue reading…

Lactose intolerance can boost the risk of diarrhea, gas and bloating. Lactose intolerance in the inability in order to digest the sugar found in whole milk. If the lactose cannot be digested, it may lead to complications like diarrhea, fuel and bloating.

Even though lactose intolerance is a harmless condition, the outward symptoms can make it quite uncomfortable for the person, leading to abdominal distress.

The enzyme lactase is manufactured in the small intestine and a deficiency leads to lactose intolerance.

With appropriate management a person with a lactose intolerance can consume some dairy and avoid the medial side effects associated with improper digestion associated with milk. Continue reading…



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Lactic intolerance Linked to Low 25-Hydroxyvitamin D Ranges – Medical News Bulletin

A new study reports that a variant in a region of DNA upstream of the human gene LCT that is linked to lactose intolerance is least common in Caucasian and most prevalent in East Asian groups. The study also found a link between lactose intolerance and reduced 25-hydroxyvitamin D (25(OH)D) levels using a 2 . 5-fold higher chance of inadequate or inadequate 25(OH)D in lactose-intolerant individuals.

Individuals with lactose intolerance are unable to digest lactose, the predominant sugar in dairy, and consequently suffer from a host of symptoms such as gas, bloating, abdominal pain, and also diarrhea. Lactose intolerance is caused by the particular deficiency of an enzyme called lactase, which is produced by the brush boundary cells in the intestine and is required for digesting lactose. While most infants create this enzyme, its production diminishes between the ages of 2-12 years in a manner that is genetically determined. Significantly lower levels of the enzyme are produced in a significant percentage of people of Africa, Asian or Hispanic descent, and this condition is also not uncommon in people of Mediterranean descent. However , in people associated with north European descent, the production of lactase largely persists into adulthood.

A stretch of GENETICS present upstream of the LCT gene, which usually codes for lactase, is considered to regulate the expression of this enzyme. In lactose-intolerant individuals, a single GENETICS base in this region at a position 13910 bases upstream of the LCT gene is really a cytosine (C) on both the maternally and paternally derived chromosomes (and therefore , called the CC genotype). However, lactose-tolerant individuals may have a combination of cytosine and thymine (CT) bases or even two thymine bases on the two chromosomes (TT).

Roughly 65% of the world population is usually thought to possess a lactose-intolerant genotype. Nevertheless , the prevalence of this genotype in the various Canadian ethnic groups has been unknown. A new study published within the Journal of Nourishment reports the distribution of the lactose-intolerant genotype in a cross-sectional group of Toronto-based individuals aged 20-29 years. Given that vitamin D fortified milk and dairy products are a major supply of the vitamin, the study also analyzed the levels of 25(OH)D (or calcidiol, an intermediate that is formed through vitamin D 3 and later converted to calcitriol, the active hormone) in the participants’ blood. The 1495 individuals who participated within the study were Caucasian (720), East Asian (506), or South Hard anodized cookware (160) with other groups constituting approximately 7% of the participants.

Information on ethnicity, health and wellness, lifestyle, dietary habits including dairy products intake, and physical activity was obtained using a questionnaire. Fasting blood samples were taken to determine the genotypes from the participants and the levels of circulating 25(OH)D. Additionally , for the 720 Caucasians within the study, the data were examined intended for possible associations between dairy intake and blood 25(OH)D concentrations throughout the three different genotypes CC, COMPUTERTOMOGRAFIE, and TT. This analysis had not been carried out for the other ethnic groupings because of small sample size or even insufficient numbers across the three genotypes or very low mean 25(OH)D concentrations.

Results showed that will in the Caucasian group, 32% of the individuals had the lactose intolerant CC genotype, whereas this number was 99%, 74%, and 59% in the East Asian, South Oriental, and other groups, respectively. Notably, the particular lactose-intolerant genotype was most common in the East Asian group, impacting nearly all of the individuals tested. Lactose intolerance was associated with a 2-fold higher risk of insufficient or inadequate 25(OH)D levels in the blood. Individuals with the COMPUTERTOMOGRAFIE genotype had a 50% higher possibility of having insufficient or inadequate bloodstream 25(OH)D levels, suggesting that these individuals could also suffer from the symptoms of lactic intolerance, which affected their consumption of vitamin D enriched dairy products.

A significant limitation of the study was that analysis linking the three LCT genotypes to 25(OH)D levels was limited to the Caucasian group, and the results of this analysis may not be applicable to other groups. Additionally , given that the study was cross-sectional in nature, the study participants may not represent the entire population.

Overall, the study provides evidence of a link among lactose intolerance and lower 25-hydroxyvitamin G levels. It also highlights the importance of making sure adequate intake of vitamin D through nondairy sources in individuals with lactose intolerance. Finally, from a public health perspective, this study highlights the importance of building up nondairy foods with vitamin D.

Written By: Usha B. Nair, Ph. D

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